Determination of the surface pathology of human sperm by atomic force microscopy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00058891" target="_blank" >RIV/00216224:14110/10:00058891 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of the surface pathology of human sperm by atomic force microscopy
Original language description
Atomic force microscopy (AFM) employs a sharp probe for profiling surfaces with unique resolution. This technique has developed into an invaluable multidisciplinary tool for advanced characterization of different samples. In its basic application, AFM provides high resolution imaging of surface structures at scales ranging from a few nanometers to hundreds micrometers. Oxidative stress is considered one of the basic etiological factors of the male?s fertility disorders. Excessive production of oxygen radicals results in damage to the sperm?s cell membrane and to the DNA. The collected AFM images clearly highlight many details of normal spermatozoa and spermatozoa damaged by hydrogen peroxide. This technique could be an important tool in the research ofoxidative stress and understanding its effect on male infertility.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FI - Traumatology and orthopaedics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NS9661" target="_blank" >NS9661: Impact of homocysteine metabolism on human infertility</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů