Melanocortin system in cancer-related cachexia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00052653" target="_blank" >RIV/00216224:14110/11:00052653 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/11:#0000149
Result on the web
<a href="http://dx.doi.org/10.2478/s11536-011-0057-6" target="_blank" >http://dx.doi.org/10.2478/s11536-011-0057-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/s11536-011-0057-6" target="_blank" >10.2478/s11536-011-0057-6</a>
Alternative languages
Result language
angličtina
Original language name
Melanocortin system in cancer-related cachexia
Original language description
The melanocortin system plays a pivotal role in the regulation of appetite and energy balance. It was recognized to play an important role in the development of cancer-related cachexia, a debilitating condition characterized by progressive body wasting associated with anorexia, increased resting energy expediture and loss of fat as well as lean body mass that cannot be simply prevented or treated by adequate nutritional support. The recent advances in understanding of mechanisms underlying cancer-related cachexia led to consequent recognition of the melanocortin system as an important potential therapeutic target. Several molecules have been made available for animal experiments, including those with oral bioavailability, that act at various checkpoints of the melanocortin system and that might confer singificant benefits for the patients suffering from cancer-related cachexia.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>
Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Central European Journal of Medicine
ISSN
1895-1058
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
5
Country of publishing house
PL - POLAND
Number of pages
8
Pages from-to
550-557
UT code for WoS article
000293708800005
EID of the result in the Scopus database
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