Optical Detection of Protein Adsorption on Doped Titanium Surface

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00054869" target="_blank" >RIV/00216224:14110/11:00054869 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Optical Detection of Protein Adsorption on Doped Titanium Surface
Original language description
The frequently used biomaterial in hard tissue replacement, such as dental and orthopaedic implants, is titanium. (Ball et al., 1996; Höök et al., 2002a; Huang et al., 2003; Imamura et al., 2008; Jones et al., 2000; Walivaara et al., 1994; Yang et al., 2003) These kind of biomaterial applications made of titanium are satisfactory products, because of their ability to adsorb certain proteins. After implantation, within a few seconds, the biomaterial surface becomes coated with a film of adsorbed proteinsmediating the interaction between the implant and the body environment. Since an implant is exposed to blood during implantation, the initial protein layer is mainly composed of plasma proteins. Human plasma fibrinogen (HPF) is the relevant protein, which adsorbs on biomaterial surfaces. HPF partakes in blood coagulation, facilitates adhesion and aggregation of platelets (Cacciafesta et al., 2001; 2000).
Czech name
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Czech description
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Project
<a href="/en/project/1M0528" target="_blank" >1M0528: Dental research centre</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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