Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00054875" target="_blank" >RIV/00216224:14110/11:00054875 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10856-011-4329-0" target="_blank" >http://dx.doi.org/10.1007/s10856-011-4329-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10856-011-4329-0" target="_blank" >10.1007/s10856-011-4329-0</a>
Alternative languages
Result language
angličtina
Original language name
Enhanced osteoblast and osteoclast responses to a thin film sputtered hydroxyapatite coating
Original language description
A sputtering technique followed by a low temperature hydrothermal treatment has been demonstrated to produce a dense-and-bioactive hydroxyapatite thin film coating. The purpose of the present study was to investigate osteoblast and osteoclast responses to the hydroxyapatite coated plates and titanium plates with similar roughness. Rat bone marrow stromal cells were cultured on these plates to induce osteoblasts. The cells showed a significantly enhanced proliferation on the hydroxyapatite surface, accompanied by increase of osteoblastic phenotypes. The co-cultured osteoclasts exhibited the significantly different cell number and morphology between the hydroxyapatite and the titanium surfaces. A series of osteoclast marker genes were more stimulated onthe hydroxyapatite and thirty two percent of the hydroxyapatite surface area could be resorbed by osteoclasts.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0528" target="_blank" >1M0528: Dental research centre</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
ISSN
0957-4530
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
6
Country of publishing house
JP - JAPAN
Number of pages
11
Pages from-to
1489-1499
UT code for WoS article
000291702500013
EID of the result in the Scopus database
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