Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00055275" target="_blank" >RIV/00216224:14110/11:00055275 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/11:#0000158

Result on the web

<a href="http://dx.doi.org/10.1038/bjc.2011.392" target="_blank" >http://dx.doi.org/10.1038/bjc.2011.392</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/bjc.2011.392" target="_blank" >10.1038/bjc.2011.392</a>

Result language

angličtina

Original language name

Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study

Original language description

Kaposi's sarcoma-associated herpes virus is associated with primary effusion lymphoma and multicentric Castleman's disease. METHODS: Seropositivity to lytic and latent Kaposi's sarcoma herpes virus (KSHV) antigens were examined in 2083 lymphomas and 2013controls from six European countries. RESULTS: Antibodies against KSHV latent and lytic antigens were detectable in 4.5% and 3.4% of controls, respectively, and 3.6% of cases (P&gt;0.05). The KSHV seropositivity was associated with splenic marginal zonelymphoma (SMZL) (odds ratio (OR) = 4.11, 95% confidence interval (CI) 1.57-10.83) and multiple myeloma (OR = 0.31, 95% CI = 0.11-0.85). CONCLUSION: The KSHV is unlikely to contribute importantly to lymphomagenesis among immunocompetent subjects. However, the observed association with SMZL may underline a chronic antigen mechanism in its aetiology.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

British Journal of Cancer

ISSN

0007-0920

e-ISSN

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Volume of the periodical

105

Issue of the periodical within the volume

11

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

1768-1771

UT code for WoS article

000297687600021

EID of the result in the Scopus database

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