Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00055577" target="_blank" >RIV/00216224:14110/11:00055577 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/1745-6215-12-13" target="_blank" >http://dx.doi.org/10.1186/1745-6215-12-13</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1745-6215-12-13" target="_blank" >10.1186/1745-6215-12-13</a>

Result language

angličtina

Original language name

Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin

Original language description

The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin. Rostafuroxin lowered blood pressure (BP) in some animal models and in humans.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Trials

ISSN

1745-6215

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

13

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

"nestrankovano"

UT code for WoS article

000286896900001

EID of the result in the Scopus database

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