Sperm and embryo analysis of similar t(7;10) translocations transmitted in two families
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00081789" target="_blank" >RIV/00216224:14110/11:00081789 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.fertnstert.2011.04.042" target="_blank" >http://dx.doi.org/10.1016/j.fertnstert.2011.04.042</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fertnstert.2011.04.042" target="_blank" >10.1016/j.fertnstert.2011.04.042</a>
Alternative languages
Result language
angličtina
Original language name
Sperm and embryo analysis of similar t(7;10) translocations transmitted in two families
Original language description
Objective: To compare the sperm meiotic segregation profiles in two men from families with similar t(7;10) translocations and determine the frequency of unbalanced sperm and preimplantation embryos in one couple. Design: Analysis of sperm nuclei and blastomeres by fluorescence in situ hybridization (FISH). Setting: Research institute. Patient(s): Carriers of balanced translocations t(7;10)(q34;q24) and t(7; 10)(q36;q24.3). Intervention(s): Multicolor FISH using probes for chromosomes 7, 10, 8, 18, 21, X, and Y on sperm and preimplantation genetic diagnosis (PGD) of blastomeres. Main Outcome Measure(s): Frequencies of meiotic segregation products in sperm and blastomeres and sperm aneuploidy of chromosomes 8, 18, 21, X, and Y. Result(s): Similar meioticsegregation patterns, with preferential alternate segregation (50.6% in patient P1, 48.1% in P2) followed by adjacent 1, adjacent 2 and 3:1 segregations, were observed in the sperm of the two carriers.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Fertility and Sterility
ISSN
0015-0282
e-ISSN
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Volume of the periodical
96
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
"E66"-"E70"
UT code for WoS article
000292283000019
EID of the result in the Scopus database
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