Complete genome sequence of Treponema pallidum strain DAL-1

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00057665" target="_blank" >RIV/00216224:14110/12:00057665 - isvavai.cz</a>

Result on the web

<a href="http://standardsingenomics.org/index.php/sigen/article/view/sigs.2615838/784" target="_blank" >http://standardsingenomics.org/index.php/sigen/article/view/sigs.2615838/784</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4056/sigs.2615838" target="_blank" >10.4056/sigs.2615838</a>

Result language

angličtina

Original language name

Complete genome sequence of Treponema pallidum strain DAL-1

Original language description

Treponema pallidum strain DAL-1 is a human uncultivable pathogen causing the sexually transmitted disease syphilis. Strain DAL-1 was isolated from the amniotic fluid of a pregnant woman in the secondary stage of syphilis. Here we describe the 1,139,971 bp long genome of T. pallidum strain DAL-1 which was sequenced using two independent sequencing methods (454 pyrosequencing and Illumina). In rabbits, strain DAL-1 replicated better than the T. pallidum strain Nichols. The comparison of the complete DAL-1genome sequence with the Nichols sequence revealed a list of genetic differences that are potentially responsible for the increased rabbit virulence of the DAL-1 strain.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/GA310%2F07%2F0321" target="_blank" >GA310/07/0321: Genomics of Treponema: comparative genome sequencing of pathogenic treponemes and transcriptome analysis of T. pallidum ssp. pallidum</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Standards in Genomic Sciences

ISSN

1944-3277

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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