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BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060622" target="_blank" >RIV/00216224:14110/12:00060622 - isvavai.cz</a>

  • Alternative codes found

    RIV/00209805:_____/12:#0000323 RIV/65269705:_____/12:#0001631

  • Result on the web

    <a href="http://dx.doi.org/10.4021/jh104e" target="_blank" >http://dx.doi.org/10.4021/jh104e</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4021/jh104e" target="_blank" >10.4021/jh104e</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B-Lineage Neoplasms

  • Original language description

    There is emerging evidence that B-lineage neoplasms have aberrant expression of B-cell activating factor (BAFF) that enables the B cells to escape apoptosis. The aim of the study therefore was to investigate circulating levels of BAFF in paediatric malignancies related to B-cell growth, i.e. B-cell acute lymphoblastic leukaemia (B-ALL) and B-lineage lymphomas. We observed significant differences in circulating levels of BAFF between the B-ALL patients and B-cell lymphoma patients (Bcp-ALL: 7764 plus-minus 6329 pg/ml, Bcell lymphoma: 2675 plus-minus 1544 pg/ml; P = 0.0268), the circulating levels of BAFF being substantially higher in B-ALL cases.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Hematology

  • ISSN

    1927-1212

  • e-ISSN

  • Volume of the periodical

    1

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CA - CANADA

  • Number of pages

    3

  • Pages from-to

    20-22

  • UT code for WoS article

  • EID of the result in the Scopus database