Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060640" target="_blank" >RIV/00216224:14110/12:00060640 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde
Original language description
For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LH12176" target="_blank" >LH12176: Benzophenanthridine alkaloids - study of their effects on cellular and molecular level</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů