LIQUID CHROMATOGRAPHY MASS SPECTROMETRY OF SELECTED BENZOPHENANTHRIDINE ALKALOIDS INCUBATED WITH RAT LIVER MICROSOMES
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00070341" target="_blank" >RIV/00216224:14110/13:00070341 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
LIQUID CHROMATOGRAPHY MASS SPECTROMETRY OF SELECTED BENZOPHENANTHRIDINE ALKALOIDS INCUBATED WITH RAT LIVER MICROSOMES
Original language description
Quaternary benzo[c]phenantridine alkaloids (QBAs) belong to a subgroup of isoquinoline alkaloids. They include major sanguinarine (SA) and chelerythrine (CHE) as well as minor QBAs chelirubine (CR), sanguilutine (SL), sanguirubine (SR), chelilutine (CL),and macarpine (MA). The effects of QBAs on biological systems have been studied extensively, especially for commercially available SA and CHE. Limited availability of the minor pentasubstituted QBAs and hexasubstituted MA reduces data concerning their biological effects. Although the QBA molecular structures are very similar, the mechanism of their action on the molecular level may be different. As pharmacological studies imply that even a small change in the structure may trigger a significant difference in pharmacological activity, it cannot be simply accepted that metabolic routes of all QBAs will be analogous.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/LH12176" target="_blank" >LH12176: Benzophenanthridine alkaloids - study of their effects on cellular and molecular level</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemické listy
ISSN
0009-2770
e-ISSN
—
Volume of the periodical
107
Issue of the periodical within the volume
Special Issue, Supplement 3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
2
Pages from-to
"S405"-"S406"
UT code for WoS article
000328730800049
EID of the result in the Scopus database
—