ISOQUINOLINE ALKALOIDS OF THE CZECH AND CHINESE CULTURE OF MACLEAYA MICROCARPA (MAXIM.) FEDDE

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00072581" target="_blank" >RIV/00216224:14110/13:00072581 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
ISOQUINOLINE ALKALOIDS OF THE CZECH AND CHINESE CULTURE OF MACLEAYA MICROCARPA (MAXIM.) FEDDE
Original language description
Macleaya microcarpa (Maxim.) Fedde belongs, together with M. cordata (Willd.) R. Br. and their interspecific hybrid Macleaya x kewensis Turill, to the genus Macleaya, family Papaveraceae. Quaternary benzophenanthridine alkaloids (QBAs) sanguinarine (SA),chelerythrine (CHE), chelirubine (CR), chelilutine (CL) and the rarely occurring macarpine (MA) are the most interesting bioactive substances. While the major benzophenanthridine alkaloids SA and CHE are available commercially and have been the subjectsof numerous biological studies, minor QBAs remained unnoticed for a long time due to their limited availability. Not long ago, first biological studies described the effects of these alkaloids on cells and identified a number of interesting properties,which puts these alkaloids in the center of interest for further research. Minor QBAs display strong anti-proliferative and apoptotic activity in vitro.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Project
<a href="/en/project/LH12176" target="_blank" >LH12176: Benzophenanthridine alkaloids - study of their effects on cellular and molecular level</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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