Potential of MR spectroscopy for assessment of glioma grading

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00067698" target="_blank" >RIV/00216224:14110/13:00067698 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/13:00060659 RIV/00023001:_____/13:00058474

Result on the web

<a href="http://dx.doi.org/10.1016/j.clineuro.2012.11.002" target="_blank" >http://dx.doi.org/10.1016/j.clineuro.2012.11.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clineuro.2012.11.002" target="_blank" >10.1016/j.clineuro.2012.11.002</a>

Result language

angličtina

Original language name

Potential of MR spectroscopy for assessment of glioma grading

Original language description

Magnetic resonance spectroscopy (MRS) is an imaging diagnostic method based that allows non-invasive measurement of metabolites in tissues. There are a number of metabolites that can be identified by standard brain proton MRS but only a few of them has aclinical significance in diagnosis of gliomas including N-acetylaspartate, choline, creatine, myo-inositol, lactate, and lipids. Results: Low-grade gliomas are generally characterized by a relatively high concentration of Nacetylaspartate, low level ofcholine and absence of lactate and lipids. The increase in creatine concentration indicates low-grade gliomas with earlier progression and malignant transformation. Progression in grade of a glioma is reflected in the progressive decrease in the N-acetylaspartate and myo-inositol levels on the one hand and elevation in choline level up to grade III on the other.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Neurology and Neurosurgery

ISSN

0303-8467

e-ISSN

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Volume of the periodical

115

Issue of the periodical within the volume

2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

8

Pages from-to

146-153

UT code for WoS article

000314447500005

EID of the result in the Scopus database

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