Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069034" target="_blank" >RIV/00216224:14110/13:00069034 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/13:#0000418
Result on the web
<a href="http://dx.doi.org/10.1186/1756-8722-6-42" target="_blank" >http://dx.doi.org/10.1186/1756-8722-6-42</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1756-8722-6-42" target="_blank" >10.1186/1756-8722-6-42</a>

Result language
angličtina
Original language name
Role of platelet chemokines, PF-4 and CTAP-III, in cancer biology
Original language description
With the recent addition of anti-angiogenic agents to cancer treatment, the angiogenesis regulators in platelets are gaining importance. Platelet factor 4 (PF-4/CXCL4) and Connective tissue activating peptide III (CTAP-III) are two platelet-associated chemokines that modulate tumor angiogenesis, inflammation within the tumor microenvironment, and in turn tumor growth. Here, we review the role of PF-4 and CTAP-III in the regulation of tumor angiogenesis; the results of clinical trial using recombinant PF-4 (rPF-4); and the use of PF-4 and CTAP-III as cancer biomarkers.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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