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Platelet-rich plasma in patients with tibiofemoral cartilage degeneration

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069554" target="_blank" >RIV/00216224:14110/13:00069554 - isvavai.cz</a>

  • Alternative codes found

    RIV/00092584:_____/13:N0000001

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s00402-013-1782-x" target="_blank" >http://dx.doi.org/10.1007/s00402-013-1782-x</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00402-013-1782-x" target="_blank" >10.1007/s00402-013-1782-x</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Platelet-rich plasma in patients with tibiofemoral cartilage degeneration

  • Original language description

    Recently an articular cartilage repair has been given much attention in the orthopaedic field. Cartilage regeneration capacity is very limited. Optimal approach seems to be a delivery of natural growth factors. Autologous platelet-rich plasma (PRP) contains proliferative and chemoattractant growth factors. The objective of the present study was to determine if PRP can increase tibiofemoral cartilage regeneration and improve knee function. Fifty consecutive and strictly selected patients, affected by Grade II or III chondromalatia, underwent 1 year treatment (9 injections) with autologous PRP in a liquid form with 2.0 to 2.5-fold platelets concentration. Outcome measures included the Lysholm, Tegner, IKDC, and Cincinnati scores. Magnetic resonance imaging was used to evaluate cartilage thickness and degree of degeneration. The study demonstrated significant improvement in Lysholm (p &lt; 0.05), Tegner (p &lt; 0.05), IKDC (p &lt; 0.05), and Cincinnati (p &lt; 0.05) scores.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FI - Traumatology and orthopaedics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT12057" target="_blank" >NT12057: Platelet-rich plasma in treatment of the chondropathy of the knee joint</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

  • ISSN

    0936-8051

  • e-ISSN

  • Volume of the periodical

    133

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    1295-1301

  • UT code for WoS article

    000323638100015

  • EID of the result in the Scopus database