Could rising BUN predict the future development of infected pancreatic necrosis?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069861" target="_blank" >RIV/00216224:14110/13:00069861 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.pan.2013.05.003" target="_blank" >http://dx.doi.org/10.1016/j.pan.2013.05.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pan.2013.05.003" target="_blank" >10.1016/j.pan.2013.05.003</a>

Result language

angličtina

Original language name

Could rising BUN predict the future development of infected pancreatic necrosis?

Original language description

Background: Infected (peri)pancreatic necrosis (IPN) in acute pancreatitis (AP) is associated with organ failure (OF) and high mortality. There are no established early markers of primary IPN. This study aimed to assess the association of simple parameters with primary IPN in AP. Methods: We retrospectively studied 281 patients with AP admitted to Mayo Clinic hospitals and identified those with microbiologically confirmed infections in (peri)pancreatic necrosis and collections. We defined primary IPN asinfection of (peri)pancreatic necrotic tissue that developed before interventions. We recorded admission hematocrit, BMI, BUN, serum creatinine, SIRS score and development of persistent organ failure within 48 h of admission; and performed serial SIRS and BUN calculations for at least 48 h. We used univariate and multivariable analysis to assess associations and expressed results as odds ratio (OR)[95% CI]. Results: 27(9.6%) patients developed IPN, of which 21(77.7%) had primary IPN. 38

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pancreatology

ISSN

1424-3903

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

5

Pages from-to

355-359

UT code for WoS article

000323464600006

EID of the result in the Scopus database

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