The EUTOS prognostic score: review and validation in 1288 patients with CML treated frontline with imatinib

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00070583" target="_blank" >RIV/00216224:14110/13:00070583 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/13:33143920 RIV/65269705:_____/13:#0002106

Result on the web

<a href="http://dx.doi.org/10.1038/leu.2013.171" target="_blank" >http://dx.doi.org/10.1038/leu.2013.171</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/leu.2013.171" target="_blank" >10.1038/leu.2013.171</a>

Result language

angličtina

Original language name

The EUTOS prognostic score: review and validation in 1288 patients with CML treated frontline with imatinib

Original language description

The introduction of tyrosine kinase inhibitors (TKI) in the treatment of Philadelphia chromosome-positive (Ph_) chronic myeloid leukemia (CML) has revolutionized the outcome, but the prognosis of the disease is still based on prognostic systems that weredeveloped in the era of conventional chemotherapy and interferon (IFN)-alfa. A new prognostic score including only two variables, spleen size and basophils, was developed for the prediction of complete cytogenetic response (CCyR) and progression-free survival (PFS). The score was based on a large series of patients who were enrolled in prospective multicenter studies of first-line imatinib treatment. The prognostic value of the EUTOS (European Treatment and Outcome Study for CML) score has now been tested in an independent, multicenter, multinational series of 1288 patients who were treated first-line with imatinib outside prospective studies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Leukemia

ISSN

0887-6924

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

10

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

2016-2022

UT code for WoS article

000325642600008

EID of the result in the Scopus database

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