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10 years of experience with thalidomide in multiple myeloma patients: Report of the Czech Myeloma Group

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00070584" target="_blank" >RIV/00216224:14110/13:00070584 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/13:#0002107 RIV/00179906:_____/13:10140041 RIV/00064173:_____/13:#0000375 RIV/00098892:_____/13:#0000484 and 3 more

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.leukres.2013.06.019" target="_blank" >http://dx.doi.org/10.1016/j.leukres.2013.06.019</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.leukres.2013.06.019" target="_blank" >10.1016/j.leukres.2013.06.019</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    10 years of experience with thalidomide in multiple myeloma patients: Report of the Czech Myeloma Group

  • Original language description

    We analyzed 1156 multiple myeloma (MM) patients treated with thalidomide. The overall response rate was 63.6%, with complete remission in 13.4%. Combined regimens had better outcomes than thalidomide plus dexamethasone or single agent thalidomide. Thalidomide was not able to overcome adverse cytogenetics. Superior results were seen in patients undergoing subsequent autologous stem cell transplantation. The rate of adverse events was low. Thalidomide has a strong potential to improve response and survival measures in patients with standard risk MM. Combined regimens should be used, with lower doses of thalidomide. High risk myelomas should be treated individually.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Leukemia Research

  • ISSN

    0145-2126

  • e-ISSN

  • Volume of the periodical

    37

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    1063-1069

  • UT code for WoS article

    000324097600014

  • EID of the result in the Scopus database