Psychosis effect on hippocampal reduction in schizophrenia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075026" target="_blank" >RIV/00216224:14110/14:00075026 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/14:00061484
Result on the web
<a href="http://dx.doi.org/10.1016/j.pnpbp.2013.10.008" target="_blank" >http://dx.doi.org/10.1016/j.pnpbp.2013.10.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.pnpbp.2013.10.008" target="_blank" >10.1016/j.pnpbp.2013.10.008</a>
Alternative languages
Result language
angličtina
Original language name
Psychosis effect on hippocampal reduction in schizophrenia
Original language description
Introduction: In schizophrenia, disruption of the neurodevelopmental processes may lead to brain changes and subsequent clinical manifestations of the illness. Reports of the progressive nature of these morphological brain changes raise questions about their causes. The possible toxic effects of repeated stressful psychotic episodes may contribute to the disease progression. Objectives: To analyze the influence of illness duration and previous psychotic episodes on hippocampal gray matter volume (GMV) in schizophrenia. Methods: We performed an analysis of hippocampal GMV correlations with illness duration, number of previous psychotic episodes, and age in 24 schizophrenia patients and 24 matched healthy controls. Results: We found a cluster of GMV voxels in the left hippocampal tail that negatively correlated with the number of previous psychotic episodes, independent from the effect of age. On the other hand we found no effect of illness duration independent of age on the hippocampal
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Progress in Neuro-Psychopharmacology and Biological Psychiatry
ISSN
0278-5846
e-ISSN
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Volume of the periodical
48
Issue of the periodical within the volume
3 Jan 2014
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
186-192
UT code for WoS article
000328074200027
EID of the result in the Scopus database
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