Increased mean platelet volume and immature platelet fraction as potential predictors of thrombotic complications in BCR/ABL-negative myeloproliferative neoplasms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077527" target="_blank" >RIV/00216224:14110/14:00077527 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/14:00061530

Result on the web

<a href="http://dx.doi.org/10.1007/s12185-014-1673-0" target="_blank" >http://dx.doi.org/10.1007/s12185-014-1673-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12185-014-1673-0" target="_blank" >10.1007/s12185-014-1673-0</a>

Result language

angličtina

Original language name

Increased mean platelet volume and immature platelet fraction as potential predictors of thrombotic complications in BCR/ABL-negative myeloproliferative neoplasms

Original language description

BCR/ABL-negative myeloproliferative neo¬plasms (MPNs) are considered to be acquired thrombo-philic conditions. Persistently enhanced platelet activation has been described in polycythaemia vera and essential thrombocythaemia (ET), and shown to contributeto a higher risk of arterial and venous thrombotic complica-tions. Recent studies have shown that mean platelet volume (MPV) and immature platelet fraction (1PF) can serve as useful markers of platelet activation and increased risk of thrombosis. The aim of the present study was to investigate the relationship between these parameters and thrombotic events in BCR/ABL-negative MPN. MPV values in patients with BCR/ABL-negative MPN were significantly higher than MPV values of healthy individuals (P &lt; 0.001). No significant difference in MPV or IPF was observed between groups of patients with and without thrombotic complications (P = 0.441; P = 0.110); the difference in IPF values was close to the significance level for patients with ET

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Hematology

ISSN

0925-5710

e-ISSN

—

Volume of the periodical

100

Issue of the periodical within the volume

5

Country of publishing house

JP - JAPAN

Number of pages

8

Pages from-to

429-436

UT code for WoS article

000345079600004

EID of the result in the Scopus database

—