Microarray analysis of mandible regionalization during mouse development
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00081215" target="_blank" >RIV/00216224:14110/15:00081215 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Microarray analysis of mandible regionalization during mouse development
Original language description
The mammalian teeth function to capture and chew food and they have become specialized for these purposes producing a complex and distinctive dentition consisting of unicuspid and multicuspid teeth. To achieve this specialization, tooth development is characterized by a complex series of reciprocal interactions that occur between the epithelium and the underlying cranial neural crest-derived mesenchyme that regulates tooth morphogenesis and differentiation at molecular level. Up to now several homeoboxgenes are known to be expressed in specific pattern of mouse mandible that specifies the incisor and molar area. However, there are still many unsolved questions how complex signaling between the epithelium and mesenchyme is regulated during initial development of different classes of teeth. To reveal these complex molecular bases of tooth development, a polygenetic approach is needed.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GB14-37368G" target="_blank" >GB14-37368G: Centre of orofacial development and regeneration</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů