Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082909" target="_blank" >RIV/00216224:14110/15:00082909 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/15:00061638

Result on the web

<a href="http://dx.doi.org/10.1155/2015/426045" target="_blank" >http://dx.doi.org/10.1155/2015/426045</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2015/426045" target="_blank" >10.1155/2015/426045</a>

Result language

angličtina

Original language name

Can Biomarkers Help to Diagnose Early Heart Failure with Preserved Ejection Fraction?

Original language description

Early heart failure with preserved ejection fraction (HFpEF) is a frequent disease, but its diagnosis is difficult and relies mostly on the evidence of left ventricular filling pressure (LVFP) elevation during exercise. Several reports have suggested that natriuretic peptides plasma levels reflect exercise-induced increase in LVFP, but they still have significant limitations. In this context, any new laboratory biomarker that can accurately reflect LVFP elevation during exercise is desirable. Recently,cardiotrophin-1, soluble endoglin, ST2, growth differentiation factor 15, galectin-3, and other new laboratory markers associated with LVFP have emerged. However, the current data on the relationship of these biomarkers and diastolic dysfunction are limited to resting conditions. Therefore, their secretion deserves to be tested under the exercise to determine their potential role in making a diagnosis of early HFpEF.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Disease Markers

ISSN

0278-0240

e-ISSN

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Volume of the periodical

2015

Issue of the periodical within the volume

"426045"

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

1-9

UT code for WoS article

000349241700001

EID of the result in the Scopus database

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