Glioblastoma Multiforme in a Patient with Isolated Hemimegalencephaly
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083712" target="_blank" >RIV/00216224:14110/15:00083712 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/15:00063576
Result on the web
<a href="http://dx.doi.org/10.1055/s-0035-1554929" target="_blank" >http://dx.doi.org/10.1055/s-0035-1554929</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0035-1554929" target="_blank" >10.1055/s-0035-1554929</a>
Alternative languages
Result language
angličtina
Original language name
Glioblastoma Multiforme in a Patient with Isolated Hemimegalencephaly
Original language description
We present an exceptional case of a patient with hemimegalencephaly and secondary intractable epilepsy treated with vagus nerve stimulation (VNS) and subsequent glioblastoma development in the hemimegalencephalic hemisphere 6 years after surgery. VNS (atage 18 years) led to a 60% reduction of intractable seizures. However, symptoms of intracranial hypertension suddenly occurred 6 years after surgery. A computed tomography scan revealed a brain tumor in the hemimegalencephalic hemisphere. Pathologic examination confirmed glioblastoma multiforme. The genetic background of hemimegalencephaly is discussed here, with attention paid to the available data about the malignant transformation of malformations of cortical development (MCDs). The case points to the need for adequate clinical and radiologic follow-up care for patients with MCDs including hemimegalencephaly.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Neurological Surgery Reports
ISSN
2193-6358
e-ISSN
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Volume of the periodical
76
Issue of the periodical within the volume
1
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
"e160"-"e163"
UT code for WoS article
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EID of the result in the Scopus database
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