Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084290" target="_blank" >RIV/00216224:14110/15:00084290 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00063352
Result on the web
<a href="http://dx.doi.org/10.1111/jog.12764" target="_blank" >http://dx.doi.org/10.1111/jog.12764</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jog.12764" target="_blank" >10.1111/jog.12764</a>
Alternative languages
Result language
angličtina
Original language name
Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging
Original language description
Aim An optimal surgical staging in the group of patients with the high-risk type of endometrial cancer is often limited by age and serious internal comorbidities. Therefore, in this study we focused on human epididymis protein 4 and its contribution to the preoperative differentiation of prognostically distinct groups of patients and to individualized surgical treatment as compared with cancer antigen (CA) 125 and imaging methods. Material and Methods The study included 115 patients with endometrioid adenocarcinoma diagnosed through endometrial biopsy. Before the final operation, blood sampling was performed for the determination of human epididymis protein 4 (HE4) and CA125 levels. Serum levels of both biomarkers were analyzed in relation to individual prognostic factors (stage of disease, depth of myometrial invasion, tumor grade, risk type of disease). Results In the case of HE4, we demonstrated a statistically significant difference (P < 0.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Obstetrics and Gynaecology Research
ISSN
1341-8076
e-ISSN
—
Volume of the periodical
41
Issue of the periodical within the volume
10
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1644-1652
UT code for WoS article
000362677500021
EID of the result in the Scopus database
—