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Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084290" target="_blank" >RIV/00216224:14110/15:00084290 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/15:00063352

  • Result on the web

    <a href="http://dx.doi.org/10.1111/jog.12764" target="_blank" >http://dx.doi.org/10.1111/jog.12764</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/jog.12764" target="_blank" >10.1111/jog.12764</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging

  • Original language description

    Aim An optimal surgical staging in the group of patients with the high-risk type of endometrial cancer is often limited by age and serious internal comorbidities. Therefore, in this study we focused on human epididymis protein 4 and its contribution to the preoperative differentiation of prognostically distinct groups of patients and to individualized surgical treatment as compared with cancer antigen (CA) 125 and imaging methods. Material and Methods The study included 115 patients with endometrioid adenocarcinoma diagnosed through endometrial biopsy. Before the final operation, blood sampling was performed for the determination of human epididymis protein 4 (HE4) and CA125 levels. Serum levels of both biomarkers were analyzed in relation to individual prognostic factors (stage of disease, depth of myometrial invasion, tumor grade, risk type of disease). Results In the case of HE4, we demonstrated a statistically significant difference (P &lt; 0.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FK - Gynaecology and obstetrics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Obstetrics and Gynaecology Research

  • ISSN

    1341-8076

  • e-ISSN

  • Volume of the periodical

    41

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1644-1652

  • UT code for WoS article

    000362677500021

  • EID of the result in the Scopus database