Automatic Evaluation of Collagen Fiber Directions from Polarized Light Microscopy Images

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084554" target="_blank" >RIV/00216224:14110/15:00084554 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26210/15:PU114247

Result on the web

<a href="http://dx.doi.org/10.1017/S1431927615000586" target="_blank" >http://dx.doi.org/10.1017/S1431927615000586</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S1431927615000586" target="_blank" >10.1017/S1431927615000586</a>

Result language

angličtina

Original language name

Automatic Evaluation of Collagen Fiber Directions from Polarized Light Microscopy Images

Original language description

Mechanical properties of the arterial wall depend largely on orientation and density of collagen fiber bundles. Several methods have been developed for observation of collagen orientation and density; the most frequently applied collagen-specific manualapproach is based on polarized light (PL). However, it is very time consuming and the results are operator dependent. We have proposed a new automated method for evaluation of collagen fiber direction from two-dimensional polarized light microscopy images (2D PLM). The algorithm has been verified against artificial images and validated against manual measurements. Finally the collagen content has been estimated. The proposed algorithm was capable of estimating orientation of some 35 k points in 15 min when applied to aortic tissue and over 500 k points in 35 min for Achilles tendon. The average angular disagreement between each operator and the algorithm was -9.3 +/- 8.6 degrees and -3.8 +/- 8.6 degrees in the case of aortic tissue and

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Microscopy and Microanalysis

ISSN

1431-9276

e-ISSN

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Volume of the periodical

21

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

863-875

UT code for WoS article

000358834600008

EID of the result in the Scopus database

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