Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00088237" target="_blank" >RIV/00216224:14110/16:00088237 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/nrmicro.2016.141" target="_blank" >http://dx.doi.org/10.1038/nrmicro.2016.141</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/nrmicro.2016.141" target="_blank" >10.1038/nrmicro.2016.141</a>

Result language
angličtina
Original language name
Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen
Original language description
The past two decades have seen a worldwide resurgence in infections caused by Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity of the syphilis spirochete for early dissemination and immune evasion has earned it the designation ‘the stealth pathogen’. Despite the many hurdles to studying syphilis pathogenesis, most notably the inability to culture and to genetically manipulate T. pallidum, in recent years, considerable progress has been made in elucidating the structural, physiological, and regulatory facets of T. pallidum pathogenicity. In this Review, we integrate this eclectic body of information to garner fresh insights into the highly successful parasitic lifestyles of the syphilis spirochete and related pathogenic treponemes.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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