Zinc and Copper Homeostasis in Head and Neck Cancer: Review and Meta-Analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00088893" target="_blank" >RIV/00216224:14110/16:00088893 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26620/16:PU126013

Result on the web

<a href="http://dx.doi.org/10.2174/0929867323666160405111543" target="_blank" >http://dx.doi.org/10.2174/0929867323666160405111543</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/0929867323666160405111543" target="_blank" >10.2174/0929867323666160405111543</a>

Result language

angličtina

Original language name

Zinc and Copper Homeostasis in Head and Neck Cancer: Review and Meta-Analysis

Original language description

Metals are known for playing essential roles in human physiology. Copper and zinc are trace elements closely dependent on one another and are involved in cell proliferation, growth, gene expression, apoptosis and other processes. Their homeostasis is crucial and tightly controlled by a resourceful system of transporters and transport proteins which deliver copper and zinc ions to their target sites. Abnormal zinc and copper homeostasis can be seen in a number of malignancies and also in head and neck cancer. Imbalance in this homeostasis is observed as an elevation or decrease of copper and zinc ions in serum or tissue levels in patients with cancer. In head and neck cancer these altered levels stand out from those of other malignancies which makes them an object of interest and therefore zinc and copper ions might be a good target for further research of head and neck cancer development and progression.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/NT14337" target="_blank" >NT14337: Study and characterization of tumour cell lines of primary squamous cell carcinoma of the head and neck and their malignant potential.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Medicinal Chemistry

ISSN

0929-8673

e-ISSN

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Volume of the periodical

23

Issue of the periodical within the volume

13

Country of publishing house

AE - UNITED ARAB EMIRATES

Number of pages

27

Pages from-to

1304-1330

UT code for WoS article

000376451300002

EID of the result in the Scopus database

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