Irreversible electroporation with endoluminal balloon catheterin perihilar region: preliminary results

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00088927" target="_blank" >RIV/00216224:14110/16:00088927 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Irreversible electroporation with endoluminal balloon catheterin perihilar region: preliminary results
Original language description
Purpose: To evaluate the safety and efficacy of endoluminal irreversible electroporation (IRE) in biliary tract performed with a balloon catheter in the perihilar region. Material and methods: Endoluminal IRE of the common bile duct was performed in 5 domestic swine using a balloon catheter inserted during laparotomy. IRE catheter consists of 3 electrodes with the length of 1 cm, attached around an inflatable balloon at 120 degrees. IRE was performed with parameters of 50-90 pulses of 1500-2000V delivered between each couple of electrodes. All swine models were slaughtered 3 days after the procedure. Imaging study using MRI and histopathologic follow-up was performed. Results: The balloon insertion and IRE procedure was successful in all porcine models. All animals survived for the designated period of 3 days. Periablation edema in hepatoduodenal ligament and adjacent liver tissue measured on postprocedural MRI ranged from 13 to 40 mm in maximum diameter, 2, 5-18, 7 ml in volumetric assessment.
Czech name
—
Czech description
—

Project
<a href="/en/project/NV15-32484A" target="_blank" >NV15-32484A: New biotechnologies in prevention and treatment of biliary tract stenosis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)