Cellular reactions of the choroid plexus induced by peripheral nerve injury
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00090251" target="_blank" >RIV/00216224:14110/16:00090251 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.neulet.2016.06.019" target="_blank" >http://dx.doi.org/10.1016/j.neulet.2016.06.019</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.neulet.2016.06.019" target="_blank" >10.1016/j.neulet.2016.06.019</a>
Alternative languages
Result language
angličtina
Original language name
Cellular reactions of the choroid plexus induced by peripheral nerve injury
Original language description
The choroid plexus (CP) of brain ventricles forms the blood-cerebrospinal fluid (blood-CSF) barrier that is involved in many diseases affecting the central nervous system (CNS). We used ED1 and ED2 immunostaining to investigate epiplexus cell changes in rat CP after chronic constriction injury (CCI). In contrast to naive CP, the CP of sham-operated rats showed an increase in the number of ED1+ cells of a similar magnitude during all periods of survival up to 3 weeks, while the number of ED2+ increased only at 3 days from operation. In comparison to naive and sham-operated animals, the number of ED1+ and ED2+ cells in the epiplexus position increased with the duration of nerve compression. We detected no or negligible cell proliferation in the CP after sham- or CCI-operation. This suggests that increased number of ED1+ and ED2+ cells in the epiplexus position of the CP is derived from peripheral monocytes passing through altered blood-CSF barrier.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroscience Letters
ISSN
0304-3940
e-ISSN
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Volume of the periodical
628
Issue of the periodical within the volume
"neuvedeno"
Country of publishing house
IE - IRELAND
Number of pages
5
Pages from-to
73-77
UT code for WoS article
000381590800012
EID of the result in the Scopus database
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