The influence of chronic application of olazapine on brain perfusion in rat
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00092302" target="_blank" >RIV/00216224:14110/16:00092302 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The influence of chronic application of olazapine on brain perfusion in rat
Original language description
Olanzapin is a commonly used atypical antipsychotic drug. We hypothesize that long term therapy of olanzapin could alter region dependent blood brain perfusion, which we tested by arterial spin labeling (ASL) MR imaging. Statistical evaluation of the ASL results in the hippocampus, somatosensory cortex and piriform cortex revealed significantly lower somatosensory cortex perfusion in olanzapin-treated animals.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů