Cognitive impairment in major depressive disorder and severe depressive episode with psychotic symptoms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F17%3A00110317" target="_blank" >RIV/00216224:14110/17:00110317 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.eurpsy.2017.01.1983" target="_blank" >http://dx.doi.org/10.1016/j.eurpsy.2017.01.1983</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.eurpsy.2017.01.1983" target="_blank" >10.1016/j.eurpsy.2017.01.1983</a>

Result language

angličtina

Original language name

Cognitive impairment in major depressive disorder and severe depressive episode with psychotic symptoms

Original language description

Introduction Cognitive impairment in patients with depressive disorder is a subject of intensive research. Objectives This study deals with the cognitive impairment in patients with severe depressive episode with psychotic symptoms and patients with major depressive disorder during the acute state of illness. Aims The aim was to define domains and the level of cognitive impairment in both groups of patients. The next aim was to compare profiles of cognitive impairment in both groups of patients. The last aim was to find out a relationship between cognitive performance and severity of depressive episode during the acute state of illness. Methods We have used neuropsychological test battery (Auditory–Verbal Learning Test, Rey-Osterrieth Complex Figure Test, Logical Memory, Digit span test, Trail making test, Verbal Fluency Test, Block Design and Benton Visual Retention Test) for the evaluation of the cognitive functions in patients with severe depressive episode with psychotic symptoms (n = 5) and patients with major depressive disorder (n = 8). Results We found cognitive impairment in all examined domains in both groups of patients. More profound cognitive impairment was found in patients with severe depressive episode with psychotic symptoms, particularly in visual memory, visuo-constructive abilities, speed of cognitive processing and executive functions. We found no correlation between cognitive performance and severity of depressive episodes. Conclusions Our findings suggest a strong correlation between psychotic symptoms in depression and cognitive performance.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

50100 - Psychology and cognitive sciences

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů