Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F18%3A00104186" target="_blank" >RIV/00216224:14110/18:00104186 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.crvasa.2017.11.006" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2017.11.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.crvasa.2017.11.006" target="_blank" >10.1016/j.crvasa.2017.11.006</a>
Alternative languages
Result language
angličtina
Original language name
Cardiac resynchronization therapy - A comparison of VV delay optimization by 3D echocardiography using systolic dyssynchrony index and QRS width assessment at 6 months after CRT implantation
Original language description
Aim: The aim of this study was to compare the setting of interventricular (VV) delay by 3D echocardiography (3DE) using systolic dyssynchrony index (SDI) versus QRS width measurement in new cardiac resynchronization therapy (CRT) recipients. We observed the impact on the reduction of left ventricle volumes and increase in volumetric responders (defined as a = 15% reduction in left ventricular end-systolic volume (LVESv)) at the 6-month follow-up. Methods: We included 63 patients with recently implanted CRT in this open-label, randomized trial. Patients were randomized into two groups. VV delay was set by the QRS width in the group 1 (n 31) to obtain the narrowest QRS complex and by SDI in the group 2 (n 32) to achieve the lowest possible value. We evaluated LVESv, left ventricular ejection fraction (LVEF) by 3DE, before CRT implantation and at 6-month follow-up, in all patients. We also obtained clinical parameters and the level of NT-proBNP. Results: The second group showed only a trend toward greater reduction of LVESv (-33 +/- 55 ml vs. -48 +/- 43 ml; P 0.367), increase in LVEF (+ 7.3 +/- 10.9% vs. + 10.2 +/- 9.4%; P 0.210) and greater number of volumetric responders (14 vs. 18; P 0.612) compared with the group 1 at 6-month follow-up. There were also no significant differences in clinical outcomes and the level of NT-proBNP. Conclusion: Individual CRT optimization using SDI compared with QRS duration assessment did not reveal any significant differences in echocardiographic parameters and clinical outcomes at 6-month follow-up. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
cor et Vasa
ISSN
0010-8650
e-ISSN
1803-7712
Volume of the periodical
60
Issue of the periodical within the volume
4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
„E367“-„E376“
UT code for WoS article
000442902500005
EID of the result in the Scopus database
2-s2.0-85037999261