Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00111775" target="_blank" >RIV/00216224:14110/19:00111775 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.hjc.2017.11.003" target="_blank" >http://dx.doi.org/10.1016/j.hjc.2017.11.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.hjc.2017.11.003" target="_blank" >10.1016/j.hjc.2017.11.003</a>
Alternative languages
Result language
angličtina
Original language name
Cardiac resynchronisation therapy optimisation of interventricular delay by the systolic dyssynchrony index: A comparative, randomised, 12-month follow-up study
Original language description
Background: The aim of our study was to compare the effect of interventricular (VV) delay optimisation in CRT recipients on the basis of systolic dyssynchrony index (SDI) derived from the three-dimensional echocardiography (3DE) versus QRS width assessment on left ventricle volume reduction at the 12-month follow-up. Methods: We included 63 patients with recently implanted CRT in this randomised, open-label trial. Patients were randomised to VV delay optimisation according to QRS complex width measurement in group 1 (n = 31) to obtain the narrowest QRS complex and SDI in group 2 (n = 32) to achieve its lowest possible value. We evaluated left ventricular end-systolic volume (LVESv), left ventricular ejection fraction (LVEF) and SDI by 3DE before CRT implantation and at a 12-month follow-up in all the patients. We also obtained the New York Heart Association functional class, the 6-minute walk test, the quality of life questionnaire and the level of NT-proBNP. Results: The number of volumetric responders was similar in both groups (17 vs. 20, P = 0.786). There were also no significant differences in the reduction of LVESv (-41 +/- 55 mL vs. - 61 +/- 51 mL, P = 0.111), improvement in LVEF (+10.1 +/- 10.6% vs. + 13.0 +/- 9.9%, P = 0.213) or differences in clinical outcomes between both groups at the 12-month follow-up. Conclusion: CRT optimisation of interventricular delay using SDI compared with QRS width assessment did not reveal any significant difference in terms of volumetric and clinical response at the 12-month follow-up. (C) 2017 Hellenic Society of Cardiology. Publishing services by Elsevier B.V.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
HELLENIC JOURNAL OF CARDIOLOGY
ISSN
1109-9666
e-ISSN
2241-5955
Volume of the periodical
60
Issue of the periodical within the volume
1
Country of publishing house
GR - GREECE
Number of pages
10
Pages from-to
16-25
UT code for WoS article
000473281500004
EID of the result in the Scopus database
2-s2.0-85044673728