Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F18%3A00106903" target="_blank" >RIV/00216224:14110/18:00106903 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/18:00068545

Result on the web

<a href="http://dx.doi.org/10.1007/s00394-016-1334-6" target="_blank" >http://dx.doi.org/10.1007/s00394-016-1334-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00394-016-1334-6" target="_blank" >10.1007/s00394-016-1334-6</a>

Result language

angličtina

Original language name

Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus

Original language description

Purpose: Gestational diabetes mellitus (GDM) represents the most frequent metabolic disorder in pregnancy. Since dietary intake plays an important role in obesity and type 2 diabetes development, it is likely to be for the susceptibility to GDM too. Food preferences, driving partly the diet composition, are changing during pregnancy. Taste and genetic variability in taste receptors is an important factor in determining food preferences. Aims of our study were (1) to characterize dietary habits of pregnant women and to find possible differences in food preferences between healthy pregnant women and those with GDM and (2) to ascertain possible association of several single nucleotide polymorphisms (SNPs) in taste receptor (TR) genes with GDM. Methods: A total of 363 pregnant women (293 with GDM and 70 with physiologic pregnancy) were included in the study. Dietary pattern spanning the period of approx. 6 months preceding the time of GDM screening was assessed using a semi-quantitative food frequency questionnaire. A total of five SNPs in TR genes were selected for genotyping based on their functionality or previous associations. Results: Women with GDM exhibited significantly more frequent meat consumption (esp. poultry, pork and smoked meat), dairy products and sweet beverages consumption. The legumes consumption was found to be inversely correlated with fasting glycaemia (P = 0.007, Spearman). CC genotype in TAS2R9 gene (SNP rs3741845) was significantly associated with GDM (P = 0.0087, Chi-square test). Conclusions: Our study showed differences in dietary intake of selected food items between healthy pregnant women and those with GDM and genetic association of bitter taste receptor allele with GDM.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30308 - Nutrition, Dietetics

Project

<a href="/en/project/NV16-28040A" target="_blank" >NV16-28040A: Long-term consequences of gestational diabetes for metabolic health of exposed women early postpartum: significance of the new diagnostic cri</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Nutrition

ISSN

1436-6207

e-ISSN

1436-6215

Volume of the periodical

57

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

513-521

UT code for WoS article

000427285000009

EID of the result in the Scopus database

2-s2.0-84991738203