MicroRNA analysis in multiple myeloma and extramedullary disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00108621" target="_blank" >RIV/00216224:14110/19:00108621 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.clml.2019.09.103" target="_blank" >http://dx.doi.org/10.1016/j.clml.2019.09.103</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.clml.2019.09.103" target="_blank" >10.1016/j.clml.2019.09.103</a>
Alternative languages
Result language
angličtina
Original language name
MicroRNA analysis in multiple myeloma and extramedullary disease
Original language description
MicroRNAs (miRNAs) are short non-coding RNA molecules that are involved in many physiological and pathological processes. Multiple myeloma (MM) is the second most common hematological malignancy of plasma cells (PCs). Survival of patients is negatively affected by extramedullary disease (EM). EM occurs when PCs migrate out of the bone marrow (BM) and lose the dependence to its microenvironment. The mechanism by which the EM occurs is not yet elucidated. The importance of miRNA in the pathogenesis of MM has been demonstrated by several studies. We assume that they are involved in the development of EM. Aims: The aim of this work was to analyze different expression of miRNA in BM PCs of EM vs MM patients.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
<a href="/en/project/NV17-29343A" target="_blank" >NV17-29343A: Bone marrow microenvironment analysis in extramedullary relapse of multiple myeloma</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů