The role of intestinal microbiota in the pathogenesis of colorectal carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00115355" target="_blank" >RIV/00216224:14110/20:00115355 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/19:A20023L9 RIV/71009396:_____/20:N0000028 RIV/61988987:17110/20:A2202CXS
Result on the web
<a href="http://dx.doi.org/10.1007/s12223-019-00706-2" target="_blank" >http://dx.doi.org/10.1007/s12223-019-00706-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12223-019-00706-2" target="_blank" >10.1007/s12223-019-00706-2</a>
Alternative languages
Result language
angličtina
Original language name
The role of intestinal microbiota in the pathogenesis of colorectal carcinoma
Original language description
The symbiotic relationship between intestinal microbiota and the host is a major mechanism of prevention against the development of chronic and metabolic diseases. The intestinal microbiota provides several physiological functions of the organism from the creation of a natural functional barrier with a subsequent immunostimulatory activity up to affecting the energy metabolism of the host. Disruption of physiological intestinal microbiota is reported as one of the major etiological factors of initiation and progression of colorectal carcinoma (CRC). Chronic low-grade inflammation is associated with the development of CRC, through the production of inflammatory cytokines and reactive oxygen species. CRC occurs in association with high-protein and high-fat diets in combination with low-fiber intake. The problem of intestinal dysbiosis and oncological diseases is a multidisciplinary problem and it is necessary to focus on several fields of medicine such as public health, clinical pharmacology, and internal medicine. The aim of this review is describing the role of gut dysbiosis in pathogenesis of colorectal carcinoma.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Folia microbiologica
ISSN
0015-5632
e-ISSN
1874-9356
Volume of the periodical
65
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
17-24
UT code for WoS article
000511921000002
EID of the result in the Scopus database
2-s2.0-85064595887