The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F20%3A00117549" target="_blank" >RIV/00216224:14110/20:00117549 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/20:00073673
Result on the web
<a href="https://www.hindawi.com/journals/omcl/2020/8877116/" target="_blank" >https://www.hindawi.com/journals/omcl/2020/8877116/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2020/8877116" target="_blank" >10.1155/2020/8877116</a>
Alternative languages
Result language
angličtina
Original language name
The Role of Oxidative Stress in Early Brain Injury after Subarachnoid Hemorrhage
Original language description
This review focuses on the problem of oxidative stress in early brain injury (EBI) after spontaneous subarachnoid hemorrhage (SAH). EBI involves complex pathophysiological mechanisms, including oxidative stress. In the first section, we describe the main sources of free radicals in EBI. There are several sources of excessive generation of free radicals from mitochondrial free radicals' generation and endoplasmic reticulum stress, to hemoglobin and enzymatic free radicals' generation. The second part focuses on the disruption of antioxidant mechanisms in EBI. The third section describes some newly found molecular mechanisms and pathway involved in oxidative stress after EBI. The last section is dedicated to the pathophysiological mechanisms through which free radicals mediate early brain injury.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Oxidative Medicine and Cellular Longevity
ISSN
1942-0900
e-ISSN
1942-0994
Volume of the periodical
2020
Issue of the periodical within the volume
NOV 2020
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
1-9
UT code for WoS article
000596448900001
EID of the result in the Scopus database
2-s2.0-85097239748