A Brief Physiology of Ion Balance in Mammal Cardiomyocytes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F22%3A00128529" target="_blank" >RIV/00216224:14110/22:00128529 - isvavai.cz</a>
Result on the web
<a href="https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2022.pdf" target="_blank" >https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2022.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A Brief Physiology of Ion Balance in Mammal Cardiomyocytes
Original language description
The muscle cells (cardiomyocytes) that make up all of the heart muscle contract in a repetitive, organized and adapted way in order to ensure the final function of circulatory support. The coordination of the contractile function is ensured thanks to the syncitium structure of the cardiac tissue which allows the propagation of the electrical activity from one cardiac cell to another. This electrical activity translates into an action potential (AP) which represents the result of a cascade of ion transfers (entry of Na+ and Ca++ ions, exit of K+ ions), largely depending on the variations in permeability of the sarcolemma and succeeding from the diastolic potential. The latter, located between -80 and -90 mV, depends on the characteristics of the sarcolemma which, at rest, is almost exclusively permeable to K+ , and on the variations in ionic concentrations (Na+ and K+ ) on either side of this membrane. However, in diastole, the sarcolemma is slightly permeable to Na+ and the concentration gradients are maintained thanks to active transport ensured by an electrogenic ATP-dependent Na+ /K+ membrane pump.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Noninvasive methods in cardiology 2022
ISBN
9788028001704
ISSN
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e-ISSN
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Number of pages
10
Pages from-to
99-108
Publisher name
Masaryk University Press
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2022
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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