Addressing Legislative and Financial Hurdles in Rare Disease Medicines Accessibility: Insight From Czechia With a Focus on the Pediatric Population
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F24%3A00138332" target="_blank" >RIV/00216224:14110/24:00138332 - isvavai.cz</a>
Result on the web
<a href="https://www.valueinhealthjournal.com/article/S1098-3015(24)04292-X/fulltext" target="_blank" >https://www.valueinhealthjournal.com/article/S1098-3015(24)04292-X/fulltext</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jval.2024.10.1429" target="_blank" >10.1016/j.jval.2024.10.1429</a>
Alternative languages
Result language
angličtina
Original language name
Addressing Legislative and Financial Hurdles in Rare Disease Medicines Accessibility: Insight From Czechia With a Focus on the Pediatric Population
Original language description
Advanced therapy medicinal products (ATMPs) and orphan drugs are vital for treating rare diseases, especially in pediatric patients. However, the reimbursement and financing system for these medicines in Czechia lacks sustainability and transparency. This study analyzes the legislative framework governing rare disease medicine reimbursement, with a focus on §16 of Act No 48/1997 Coll. regarding exceptional reimbursement cases. Data from University Hospital Brno highlight the growing reliance on §16, with approval rates for pediatric patients increasing dramatically between 2017 and 2021. Despite high approval rates, the overuse of §16 undermines the need for legislative reform. Significant gaps, such as impractical cost-effectiveness analysis (CEA) requirements, hinder transparency and equitable access. The findings emphasize the urgent need for legislative reforms to ensure a predictable, sustainable, and fair reimbursement system for ATMPs and orphan drugs, particularly benefiting pediatric patients.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30200 - Clinical medicine
Result continuities
Project
<a href="/en/project/LM2023049" target="_blank" >LM2023049: Czech National Node of the European Clinical Research Infrastructures Network</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů