Effect of Quarantine Strategies in a Compartmental Model with Asymptomatic Groups

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F24%3A00138892" target="_blank" >RIV/00216224:14110/24:00138892 - isvavai.cz</a>
Alternative codes found
RIV/47813059:19610/24:A0000156
Result on the web
<a href="https://link.springer.com/article/10.1007/s10884-021-10059-5" target="_blank" >https://link.springer.com/article/10.1007/s10884-021-10059-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10884-021-10059-5" target="_blank" >10.1007/s10884-021-10059-5</a>

Result language
angličtina
Original language name
Effect of Quarantine Strategies in a Compartmental Model with Asymptomatic Groups
Original language description
We present an epidemiological model, which extend the classical SEIR model by accounting for the presence of asymptomatic individuals and the effect of isolation of infected individuals based on testing. Moreover, we introduce two types of home quarantine, namely gradual and abrupt one. We compute the equilibria of the new model and derive its reproduction number. Using numerical simulations we analyze the effect of quarantine and testing on the epidemic dynamic. Given a constraint that limits the maximal number of simultaneous active cases, we demonstrate that the isolation rate, which enforces this constraint, decreases with the increasing testing rate. Our simulations show that massive testing allows to control the infection spread using a much lower isolation rate than in the case of indiscriminate quarantining. Finally, based on the effective reproduction number we suggest a strategy to manage the epidemic. It consists in introducing abrupt quarantine as well as relaxing the quarantine in such a way that the epidemic remains under control and further waves do not occur. We analyze the sensitivity of the model dynamic to the quarantine size, timing and strength of the restrictions.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30230 - Other clinical medicine subjects

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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