Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases-A Review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00131344" target="_blank" >RIV/00216224:14160/23:00131344 - isvavai.cz</a>
Result on the web
<a href="https://mdpi-res.com/d_attachment/molecules/molecules-28-00158/article_deploy/molecules-28-00158-v2.pdf?version=1672141957" target="_blank" >https://mdpi-res.com/d_attachment/molecules/molecules-28-00158/article_deploy/molecules-28-00158-v2.pdf?version=1672141957</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/molecules28010158" target="_blank" >10.3390/molecules28010158</a>
Alternative languages
Result language
angličtina
Original language name
Therapeutic Potential of Flavonoids and Tannins in Management of Oral Infectious Diseases-A Review
Original language description
Medicinal plants are rich sources of valuable molecules with various profitable biological effects, including antimicrobial activity. The advantages of herbal products are their effectiveness, relative safety based on research or extended traditional use, and accessibility without prescription. Extensive and irrational usage of antibiotics since their discovery in 1928 has led to the increasing expiration of their effectiveness due to antibacterial resistance. Now, medical research is facing a big and challenging mission to find effective and safe antimicrobial therapies to replace inactive drugs. Over the years, one of the research fields that remained the most available is the area of natural products: medicinal plants and their metabolites, which could serve as active substances to fight against microbes or be considered as models in drug design. This review presents selected flavonoids (such as apigenin, quercetin, kaempferol, kurarinone, and morin) and tannins (including oligomeric proanthocyanidins, gallotannins, ellagitannins, catechins, and epigallocatechin gallate), but also medicinal plants rich in these compounds as potential therapeutic agents in oral infectious diseases based on traditional usages such as Agrimonia eupatoria L., Hamamelis virginiana L., Matricaria chamomilla L., Vaccinium myrtillus L., Quercus robur L., Rosa gallica L., Rubus idaeus L., or Potentilla erecta (L.). Some of the presented compounds and extracts are already successfully used to maintain oral health, as the main or additive ingredient of toothpastes or mouthwashes. Others are promising for further research or future applications.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
MOLECULES
ISSN
1420-3049
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
21
Pages from-to
1-21
UT code for WoS article
000909925400001
EID of the result in the Scopus database
2-s2.0-85145713736