Novel fluorophores applicable for glycan detection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00132382" target="_blank" >RIV/00216224:14160/23:00132382 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Novel fluorophores applicable for glycan detection
Original language description
Changes in the composition of glycans correlate with the progression of many diseases; therefore, they are investigated as disease markers. Unfortunately, their analysis is complicated because they do not contain a chromophore or charges that would enable their electrophoretic separation. Our idea was to develop a new fluorescent marker covalently bound to glycans providing fast labeling kinetics, high quantum yield, increased detection sensitivity using MS, and at the same time, carrying a charge in the structure, which will enable the studied glycans to be separated electrophoretically
Czech name
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Czech description
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Project
<a href="/en/project/GA22-00236S" target="_blank" >GA22-00236S: Development of novel fluorescent labeling tags for electrophoretic analysis of glycoproteins associated with breast cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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