Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00132828" target="_blank" >RIV/00216224:14160/23:00132828 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus
Original language description
Staphylococcus aureus has a broad virulence capacity and biofilm formation limits the control of wound infections. Paulownia tomentosa Steud. (Paulowniaceae) is a rich source of geranylated phenolics responsible for various bioactivities. Ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity. In combination with fusidic acid and mupirocin, synergistic potential was observed. Membrane disruption is partly responsible for the antimicrobial activity of geranylated flavonoids. Selected plant formulations reduced the adhesion of bacteria to the abiotic surface, and also the inhibition of intercellular communication and quorum-sensing was described.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů