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PID2022-137372OR-C2: Novel antivirals against West Nile virus (WNV) infection targeting key events in viral replication and cellular factors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00133330" target="_blank" >RIV/00216224:14160/23:00133330 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    PID2022-137372OR-C2: Novel antivirals against West Nile virus (WNV) infection targeting key events in viral replication and cellular factors

  • Original language description

    West Nile virus (WNV) infection causes febrile, sometimes very serious and even fatal diseases. The outbreak of the virus includes Africa, Middle East, West Asia, Australia, North America, but it has also spread to southern, eastern or western Europe. The infection is transmitted via the bite of infected mosquitoes. In more than three-quarters of cases, the infection is asymptomatic, however, flu-like symptoms are observed in approx. 20% of those infected and, in some cases, severe neurological symptoms can develop, which can end fatally. Unfortunately, there is still no specific treatment, so this project focuses on the identification of new molecules that could be used as new substances with an antiviral effect.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů