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Optimization and validation of a rapid HPLC-ELSD method for carbohydrates analysis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F24%3A00137470" target="_blank" >RIV/00216224:14160/24:00137470 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.faf.cuni.cz/getattachment/Special/SAL2024/Program/SAL_2024_Book_of_Abstracts_v2.pdf.aspx?lang=en-GB" target="_blank" >https://www.faf.cuni.cz/getattachment/Special/SAL2024/Program/SAL_2024_Book_of_Abstracts_v2.pdf.aspx?lang=en-GB</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Optimization and validation of a rapid HPLC-ELSD method for carbohydrates analysis

  • Original language description

    A healthy lifestyle is a common trend these days and the consumption of food supplements is part of this lifestyle. These dietary supplements are usually composed of carbohydrates as a fast energy source (fructose, glucose, sucrose) and a slow energy source (Palatinose, maltodextrins). As excipients in pharmaceutical forms (lactose) and as a functional drug (lactulose), sugars are an integral part of pharmacy. HPLC (High Performance Liquid Chromatography) in a HILIC (Hydrophilic Interaction Liquid Chromatography) mode with a polyhydroxy stationary phase can by advantageously used for carbohydrates separation and determination. The ELS (Evaporative Light-Scattering) detector is an alternative to the well-known refractive index for analytes without a suitable UV-Vis chromophore.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30107 - Medicinal chemistry

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů