Development, optimization, and evaluation of thymol-loaded self-micro emulsifying drug delivery system
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F24%3A00139403" target="_blank" >RIV/00216224:14160/24:00139403 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Development, optimization, and evaluation of thymol-loaded self-micro emulsifying drug delivery system
Original language description
Thymol as a drug with low bioavailability is a promising candidate for self-micro emulsifying drug delivery systems (SMEDDS). This study aimed to develop a thermodynamically stable thymol-loaded SMEDDS for potential adsorption onto a solid carrier for capsule filling. The formulated system exhibited stability under challenging conditions and demonstrated effective intestinal membrane penetration. Further research will focus on its long-term stability and solidification.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/GA22-03187S" target="_blank" >GA22-03187S: Rational Design of Polysaccharide‐based Particulate Systems for the Delivery of Mucosal Therapeutics with Broad Spectrum of Biological Activities</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů