Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F25%3A00142912" target="_blank" >RIV/00216224:14160/25:00142912 - isvavai.cz</a>
Result on the web
<a href="https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf" target="_blank" >https://www.sfd.si/cespt2025/wp-content/uploads/2020/08/15-cespt-konferenca-book-of-2025-1.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics
Original language description
Natural mucoadhesive polymers, such as sodium alginate, have garnered significant research attention for their beneficial properties in developing modern dosage forms, including vaginal drug delivery for infections treatment. Sodium alginate can form polymer hydrogel particles through external ionic gelation with safe cross-linking ions like Ca2+ [1]. These polymer carriers can serve as vehicles to incorporate biologically active natural substances derived from plant sources such as thymol, eugenol, and carvacrol. Their combinations may exhibit synergistic effects that hold promise in combating infectious diseases [2]. By integrating these substances into mucoadhesive polymers, we can leverage their effects when applied to mucous membranes. This study will explore the antimicrobial synergistic impact of these aforementioned phytotherapeutics against Escherichia coli (E. coli).
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů