Silver Electrode as a Sensor for Determination of Zinc in Cell Cultivation Medium

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F02%3A00005423" target="_blank" >RIV/00216224:14310/02:00005423 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Silver Electrode as a Sensor for Determination of Zinc in Cell Cultivation Medium
Original language description
Use of the silver electrode as a sensor for monitoring of zinc in cell growth medium is described. Zinc at siver electrodes provides specific voltammetric signal, which is affected by solution components. Signlas of zinc ions in phosphate buffer solutions with and without cell growth meidum were compared. Common DMEM cell culture medium was used for the cultivation of a cell line of v-myb-transformed chicken monoblasts and its variants expressing v-jun and c-jun in a zinc dependent manner. Electrochemical results showed zinc concentrations in the medium coincide very well with the jun expression. With respect to the low toxicity of xilver for eukaryotic cells, silver electrodes represent promising tools for the determination of zinc concentrations in vivo without the potential risk of a cell culture damage.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CG - Electrochemistry
OECD FORD branch
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Project
<a href="/en/project/GV204%2F97%2FK084" target="_blank" >GV204/97/K084: Electrodes modified with nucleic acids and proteins.New tools in biochemical and biomedical research.</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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