Mycobacterial glycosyltransferases: fold recognition analysis of the Mycobacterium tuberculosis genome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F02%3A00007110" target="_blank" >RIV/00216224:14310/02:00007110 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Mycobacterial glycosyltransferases: fold recognition analysis of the Mycobacterium tuberculosis genome
Original language description
Mycobacterium tuberculosis is a pathogen that is resistant to most common antibiotics and chemotherapeutic agents. This resistance is related to an unusual and well-organized structure of the mycobacterial cell wall that shows an abnormally low degree ofthe hydrophilic permeability. Outer cell wall contains the biochemically unique structures of sugar residues, constituents of various branched and complex polysaccharides and glycolipids . There is very little knowledge about the biosynthesis pathways of these glycoconjugates and about the enzymes, especially glycosyltransferases (GT), involved. The genome of M. tuberculosis contains 3,951 protein-coding sequences. Putative function annotation of some of them was predicted using a combination of sequence alignment and motif comparison . Using this approach, only a small number of putative GTs was identified. Recent crystal structure determination of GTs demonstrated that they adopt only a limited number of topology . We focused on 3D-t
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LN00A016" target="_blank" >LN00A016: BIOMOLECULAR CENTER</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XIXčmes Journées de Chimie et Biochimie des Glucides
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
65
Publisher name
Societe francaise de Chimie
Place of publication
France
Event location
May 20 - 24, Albe, France
Event date
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Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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