NMR Relaxation Studies of Fast Internal Motions in Nucleic Acids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F03%3A00009533" target="_blank" >RIV/00216224:14310/03:00009533 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

NMR Relaxation Studies of Fast Internal Motions in Nucleic Acids

Original language description

Internal motions of two 14-nt RNA hairpins containing UUCG and GCAA tetraloops were studied by C-13 NMR relaxation and molecular dynamics. While both tetraloops exhibit an increased mobility on the fast time scale, with the GCAA loop we have detected a significant contribution of conformational dynamics on the millisecond to microsecond time scale. This is consistent with the observation that the GNRA family of tetraloops appears more flexible and tolerant of the conformational changes important for molecular recognition.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

<a href="/en/project/LN00A016" target="_blank" >LN00A016: BIOMOLECULAR CENTER</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Materials Structure

ISBN

1211-5894

ISSN

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e-ISSN

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Number of pages

2

Pages from-to

40-41

Publisher name

Czech and Slovak Crystalographic Association

Place of publication

Prague

Event location

Nové Hrady

Event date

Mar 15, 2003

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

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